lunes, 27 de junio de 2011

Celiaquia y Deficiencia de Magnesio (inglés)

Interesante articulo del Dr. Osborne de la pagina web Gluten Free society, muestra como la deficiencia de un nutriente puede geneara una cascada de transtornos en el organismo.

Gluten Sensitivity and Magnesium Deficiency

Most people are aware that gluten can induce malabsorption of nutrients. Gluten can cause damage to intestinal cells can reduce the production of digestive enzymes that help break down foods and aid in nutrient absorption. Additionally, it can contribute to villous atrophy, leaky gut syndrome, and diarrhea. All of these issues are associated with poor nutritional absorption.

The following video discusses the causes and consequences of magnesium deficiency. Lack of this mineral is extremely common in those with food intolerance issues, and often times the symptoms mimic other diseases.
Singns & Symptoms of Magnesium Deficiency:
  • Poor immune function
  • Bone Loss
  • Muscle pain and muscle twitching
  • Depression
  • High Blood Pressure
  • Increase cholesterol
  • Hypoglycemia or other blood sugar problems
  • Fatigue
  • Thyroid Disease

Magnesium has been shown to be beneficial in the following conditions:

Drugs or additives that may deplete or interfere with metabolism:

  • Alcohol
  • Corticosteroids
  • High Blood Pressure Medications (diuretics)
  • Caffeine
  • Birth Control Pills (estrogen)

Laboratory Testing:

  • Lymphocyte proliferation assays (Spectracell labs)
  • Red Blood Cell testing
  • Serum testing (not accurate)

Food Sources:


Vegetables and fruits, pumpkin seeds (very high)
http://www.glutenfreesociety.org/gluten-free-society-blog/gluten-sensitivity-and-magnesium-deficiency/

lunes, 20 de junio de 2011

Adherencia a las Guias de Diagnóstico para Celiaquia

Adherencia a las Guias de Diagnóstico para Celiaquia
Resumen
La celiaquia es un trastorno común pero sub diagnosticado en USA. La recomendación propuesta es la de realizar 4 muestras de tejido de la biopsia duodenal. La adherencia a esta recomendacion son desconocidas.

Los resultados del estudio mostraron una baja adherencia a las recomendaciones fueron en el 2009 de 37%.  Con 4 biopsias intestinales se duplica el diagnostico de celiaquia, en comparación con los resultados obtenidos en menos de 4 muestras.
Por ello resulta importante mantener la adherencia a la recomendación médica de obtener 4 muestras de duodeno para obtener un  mejor diagnostico de celiaquia, hasta que nuevas formas de obtención del diagnóstico se investiguen.
:_________________________________
Adherence to biopsy guidelines increases celiac disease diagnosis  
Benjamin Lebwohl MD, MS , Robert C. Kapel MD, Alfred I. Neugut MD, PhD, Peter H.R. Green MD and Robert M. Genta MD

Background

Celiac disease (CD) is common but underdiagnosed in the United States. A proposed quality guideline recommends that ≥4 specimens be submitted during duodenal biopsy. The degree of adherence to this recommendation in clinical practice is unknown.

Objective

To measure the number of specimens submitted during duodenal biopsy among patients throughout the United States and to determine the incremental diagnostic yield of adherence to the recommended number of specimens.

Design

Retrospective cohort study.

Patients

This study involved 132,352 patients without known CD who underwent duodenal biopsy.

Intervention

Duodenal biopsy.

Main Outcome Measurements

Duodenal biopsy specimens were submitted to a pathology laboratory operating in 43 states in the United States. We used multivariate logistic regression to identify factors associated with submitting ≥4 specimens. We also compared the prevalence of newly diagnosed CD in biopsies with ≥4 specimens with that in biopsies with <4 specimens.

Results

Of the 132,352 patients who underwent biopsy (67% women, mean age 52.9 years), ≥4 specimens were submitted in 45,995 cases (35%). A modest increase in the proportion of biopsies with ≥4 specimens occurred after this guideline was proposed in 2006 (odds ratio for 2009 vs 2006, 1.51; 95% confidence interval, 1.22-1.88), but the rate of adherence in 2009 remained low at 37%. Among patients in whom the indication was malabsorption/suspected CD (n = 3261), adherence to this standard was only 39.5%. The probability of a new diagnosis of CD was increased when ≥4 specimens were submitted (1.8% vs 0.7%; P < .0001).

Limitations

Retrospective analysis lacking clinical follow-up. The guideline publication occurred during the study period, possibly influencing clinical practice and confounding results.

Conclusion

Although this proposed standard remains a subject of debate, adherence to submitting ≥4 specimens is low in the United States. Adherence yields a diagnosis rate of 1.8%, a small absolute increase but a doubling of the diagnosis rate of CD. Efforts to increase adherence are warranted.
Abbreviations: CD, celiac disease
http://www.sciencedirect.com/science/article/pii/S0016510711015136

miércoles, 15 de junio de 2011

Esquizofrenia, gluten, bajos carbohidratos y dieta cetogénica: caso y revi literatura

Abstract



Reportamos la resuolución inesperada de los sítomas crónicos de la esquizofrenia, después de empezar una dieta cetogénica con bajo contenido de carbohidratos.  Luego de la revisión de litaratura, las posibles razones a estos resultados incluyen a las consecuencias metabólicas de la eliminación del gluten de la dieta, y la modulación de la enfermedad a un nivel celular.
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We report the unexpected resolution of longstanding schizophrenic symptoms after starting a low-carbohydrate, ketogenic diet. After a review of the literature, possible reasons for this include the metabolic consequences from the elimination of gluten from the diet, and the modulation of the disease of schizophrenia at the cellular level.

Ver atículo completo (ingles)
http://www.nutritionandmetabolism.com/content/6/1/10

viernes, 10 de junio de 2011

11 Junio Conferencia Celiaquia

El Dia de mañana Sábado la Asociación participará en el II Congreso Internacional de Consultoría Nutricional organizado por NUTRAVIDA, brindando la conferencia Celiaquia y Manejo Nutricional, en el auditorio del Colegio Médico (Av. 28 de Julio cdra. 7 cruce con Grimaldo del Solar Miraflores)  a las 5:00pm.
http://www.nutravidaciens.com/portal/index.php?option=com_content&view=article&id=63:ii-congreso-internacional-de-consultoria-nutricional&catid=40:spotlight&Itemid=67 

Saludos
Geraldine